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Additional file 8: Table S1. of Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration

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posted on 2015-09-02, 05:00 authored by Aurélie Ghaye, David Bergemann, Estefania Tarifeño-Saldivia, Lydie Flasse, Virginie Von Berg, Bernard Peers, Marianne Voz, Isabelle Manfroid
Duct-specific genes listed by decreased expression level. We found 293 genes corresponding to the following “specificity” criteria: gene expression level normalized counts >1000 in duct and <1000 in non-ductal (averaged endocrine and acinar) transcriptome and ≥16 fold enrichment in ducts versus non-duct (averaged endocrine and acinar), expressed in log2 ratio (≥4). Ratio is mean of normalized counts in duct transcriptomes/mean of normalized counts in endocrine and in acinar transcriptomes. Known ductal markers and genes involved in the Notch pathway are highlighted in red. Novel markers and genes involved in the Wnt pathway are highlighted in green. (DOCX 26 kb)

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