Additional file 7 of Integrative DNA methylation and gene expression analysis to assess the universality of the CpG island methylator phenotype

Association between CIMP and clinical annotations. Panel A. Association between CIMP and age: distribution of patients’ age given their CIMP phenotype in each tissue. Panel B. Association between CIMP and MSI in colon: ratio of MSI-positive and MSI-negative patient given the CIMP phenotype in the colon. Panel C. Association between CIMP and ER status in breast: ratio of ER-positive patients given the CIMP phenotype in the breast. Panel D. Association between CIMP and PR status in the breast: ratio of PR-positive patients given the CIMP phenotype in the breast. Panel E. Association between CIMP and HER2 status in the breast: ratio of HER2-positive patients given the CIMP phenotype in the breast. (PDF 86 kb)