Additional file 6: Figure S4. of The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling

Characterization of osteogenic and chondrogenic potential of FOP iECs. Gene expression analysis of SMA, SOX9, MMP10, SP7, and RUNX2 by qPCR of WT and FOP iECs. None of these gene expression levels were statistically different by Student’s t test. Error bars represent mean ± one standard deviation of at least three independent replicates for each of the three WT and four FOP iEC lines. (TIF 158 kb)