Additional file 5: of SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis

Fig. S5. The xenografted tumor volume of DU145 stable cell lines in nude mice. The DU145 stable cell lines were injected subcutaneously into male BALB/c nude mice. 5 male BALB/c nude mice were injected subcutaneously with stable DU145 cell lines (2.5 × 106 cells/each) expressing the shRNA control vector in the left back and shKHSRP in the right back, respectively. Another 5 male BALB/c nude mice were injected subcutaneously with stable DU145 cell lines expressing shKHSRP-KHSRP WT in the left back and shKHSRP-KHSRP K87R in the right back, respectively. The sizes of tumors were measured at 15, 21, 27 and 32 days after injection (PDF 546 kb)