Additional file 4: of Genome analysis of E. coli isolated from Crohn’s disease patients

(A) Mauve alignment of CD-E. coli isolates from one patient (alignment made for RCE01, RCE02, RCE03, RCE03 and RCE06). (B) Heatmap of the phylogenetic distance between E. coli strains. Distances between strains are calculated as the median distance of core genes (see Methods). Phylogroups of E. coli are designated (A, B1, E, B2, D, F). RCE03 is not shown because of its low similarity to other E. coli strains. (DOC 4350 kb)