## Additional file 4 of Choice of futility boundaries for group sequential designs with two endpoints

2017-08-08T05:00:00Z (GMT) by
Probability of stopping for futility and overall power for Approach 3. Plot of probability of stopping for futility (left figure) and overall power (right figure) for Approach 3 using the futility β γ-boundaries α f CE = 0.69 $\alpha_{f}^{CE}=0.69$ and α f MC = 0.65 $\alpha_{f}^{MC}=0.65$ for composite endpoint and main component, respectively. (JPG 202 kb)