12974_2017_1037_MOESM4_ESM.tif (3.52 MB)

Additional file 4: Figure S4. of Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model

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posted on 04.01.2018 by Xi Jiang, Lexing Xu, Lin Tang, Fuhe Liu, Ziwei Chen, Jiajia Zhang, Lei Chen, Cong Pang, Xuefeng Yu
Effects of IDO inhibitor 1-MT (1, 3 mg/kg) on KYN/TRY ratio in the hippocampus (A) and cerebral cortex (B), and 5-HT/TRY ratio in the hippocampus (C) and cerebral cortex (D) of BDL rats. Data are expressed as mean ± SEM (n = 6). *p < 0.05, **p < 0.01 and ***p < 0.001 when compared to the sham group, #p < 0.05 when compared to the BDL group. (TIFF 3600 kb)


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