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Additional file 3: Table S2. of Hormetic effect of rotenone in primary human fibroblasts

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posted on 2015-09-16, 05:00 authored by Shiva Marthandan, Steffen Priebe, Marco Groth, Reinhard Guthke, Matthias Platzer, Peter Hemmerich, Stephan Diekmann
The most significant commonly up- and down-regulated genes in primary human fibroblast strains independent of their cell origin. The common genes most significantly differentially regulated at transcript levels in low dose rotenone treated MRC-5 (PDs 42, 48) and HFFs (PDs 26, 30, 34) compared to untreated controls. These genes were selected according to the statistical stringency criteria of p < 0.05 and adherence with both statistical packages (DESeq and edgeR). (DOCX 20 kb)

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JenAge funding by the German Ministry for Education and Research (Bundesministerium für Bildung und Forschung – BMBF)

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    Immunity & Ageing

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    down-regulated genesDOCX 20 kbstringency criteriaHFFPDfibroblast strainsdose rotenoneHormetic effecttranscript levelsMRCcell origin

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