Additional file 2: of Selective activation of TNFR1 and NF-κB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells

The effect of KC-53 on the survival of various human cancer cell lines, on PBMCs and on the immortalized “normal” cell line, MCF-12 F. Cells were exposed to increasing concentrations (0–60 μΜ) of KC-53 for 48 h. Cell survival was determined with the MTT cell viability assay and is expressed as percentage of survival compared to vehicle controls. The results represent the mean ± SEM of three replicates and are representative of at least three different experiments. (TIF 54 kb)