Additional file 2: Figure S2. of Complement activation at the motor end-plates in amyotrophic lateral sclerosis

Representative confocal immunofluorescence for synaptophysin (SYN-Cy3) detecting the motor nerve terminal (A, B) or S100b (Cy3) detecting the terminal Schwann cells (C, D) double stained with an antibody detecting MAC (FITC) in control (A, C) and ALS (B, D) intercostal muscle shows MAC deposition on both the motor nerve terminal and the terminal Schwann cells (white arrow in B and D, respectively) but no MAC deposition in controls. (TIF 2178 kb)