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Additional file 2: Figure S1. of Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer

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posted on 2017-02-01, 05:00 authored by Sara Duhachek-Muggy, Yue Qi, Randi Wise, Linda Alyahya, Hui Li, Jacob Hodge, Anna Zolkiewska
ADAM12 mRNA is upregulated in claudin-low breast cancers. a Heatmap showing ADAM12 mRNA expression levels in 295 breast cancer patients from the Netherlands Cancer Institute (NKI) database [31]. Molecular subtypes of tumors are: B, basal; CL, claudin-low; HER2+, HER2-enriched; LumA, luminal A; LumB, luminal B; NL, normal-like. b Expression levels of ADAM12 in 508 breast cancer patients from The Cancer Genome Atlas (TCGA, Nature 2012 dataset) [33]. (TIF 4437 kb)

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National Cancer Institute

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    Molecular Cancer

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    Breast cancerCancer stem cellsEpidermal growth factor receptorEpithelial-to-mesenchymal transitionADAM metalloprotease

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