Additional file 1: Table S1. of Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies

Hüls, Anke; Krämer, Ursula; Carlsten, Christopher; Schikowski, Tamara; Ickstadt, Katja; Schwender, Holger

doi:10.6084/m9.figshare.5709304.v1

12863_2017_586_MOESM1_ESM.docx (405.23 kB)

Additional file 1: Table S1. of Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies

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posted on 2017-12-16, 05:00 authored by Anke Hüls, Ursula Krämer, Christopher Carlsten, Tamara Schikowski, Katja Ickstadt, Holger Schwender

Simulated predominant interaction effects (example data for N = 3000). Table S2. Simulated marginal genetic effects (example data for N = 3000). Comparison of GRS approaches and lasso regression. Figure S1. Power and sign-misspecifications comparison. Figure S2. Type I error comparison. (DOCX 405 kb)

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Polygenic approach Training dataset Internal weights External weights Simulation study Power Type I error

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Additional file 1: Table S1. of Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies

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