Additional file 1: Figure S1. of Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster

Alignment of the amino acid sequences of several insects and mammalian PFKs. The putative residues assigned to the binding of effectors/substrates are indicated. α - F6P; β - ATP substrate; χ - ATP inhibitor; δ - citrate; ε - F2, 6BP ϕ - AMP. The sequences shown are from: Oryctolagus cuniculus (ORYCU), Mus musculus (MUSMU), Homo sapiens (HOMSA), Aedes aegypti, (AEDAE), Culex quinquefasciatus (CULPI), Anopheles gambiae, ANOGA), Drosophila melanogaser (DROME), Drosophila virilis (DROVI), Drosophila pseudoobscura (DROPE), Acyrthosiphon pisum, (ACYPI), Tribolium castaneum, (TRICA), Pediculus humanus corporis (PEDHU), Bombus terretris (BOMTE), Rhodnius prolixus (RPRC). (TIF 9895 kb)