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Additional file 10: Figure S4. of Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients

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posted on 2016-10-04, 05:00 authored by Thomas Southworth, Jonathan Plumb, Vandana Gupta, James Pearson, Isabel Ramis, Martin Lehner, Montserrat Miralpeix, Dave Singh
Representative images for Immunohistochemistry negative controls. Bronchial biopsy tissue was stained using primary antibodies against PI3Kδ, PI3Kγ, pAKT, STAT1, STAT3, STAT5 and STAT6. Sequential sections were used for negative controls using either an isotype control negative antibody at the same concentration as the various primary antibodies, or with the omission of the primary antibody. Negative controls for each primary antibody were assessed in sequential tissue sections from n = 3 patients. Black bar represents 100 μm. (PPTX 487 kb)

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