Absence of the ploidy effect in PMC size distribution.

(A–C) Optimization of the parameter t in our model with k = 0.5 based on the RSS value to estimate the ploidy profile of PMCs in WT (A) and the ploidy profile thus determined (B). Experimentally determined (Exp.) and mathematically modeled (mod.) probabilities of 2C (green), 4C (blue), 8C (orange), 16C (red), and 32C (black) are shown. (C) Histogram of the measured size of the PMCs (blue bars) and the estimated cell size distribution with the ploidy effect (+PE, black dots with solid line) or without (-PE, magenta dots with solid line).