posted on 2016-11-01, 17:52authored byFathul Huda, Yiping Fan, Mamiko Suzuki, Ayumu Konno, Yasunori Matsuzaki, Nobutaka Takahashi, Jerry K. Y. Chan, Hirokazu Hirai
Four-week-old and 6–8-month-old wild-type (WT) and SCA1 mice that were treated with the Tet-off system (Tables 1 and 2) were analyzed. All mice were incubated more than 2 weeks and, therefore, those that did not show GFP (+) cells at the time of microscopic observation were regarded as fusion-negative mice. Number on each bar shows number of mice with GFP (+) cells / that of mice examined. Fisher’s exact test showed significantly higher emergence of GFP-positive cells in 6–8-month-old SCA1 mice than 4-week-old and 6–8-month-old wild-type mice and 4-week-old SCA1 mice. **p<0.01, ***p<0.001.