Fig 6.TIF (2.58 MB)
A subset of PAAR-like proteins is extended by T6SS effector domains.
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posted on 2016-09-07, 04:30 authored by Mélanie Rigard, Jeanette E. Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, Lena Lindgren, Claire Punginelli, Claire Lays, Olivier Walker, Alain Charbit, Philippe Telouk, Wayne Conlan, Laurent Terradot, Anders Sjöstedt, Thomas HenryThe 10 most prevalent domain architectures of DUF4280-containing proteins are shown. Data were retrieved from CDART using the IglG protein sequence as input. The name of the DUF4280-associated domain (and when required a short description) is given below together with the superfamily accession number. Lysozyme-like superfamily (cl00222); NLpC_P60 (cl21534), a family of cell-wall peptidases [40]; Esterase-lipase superfamily (cl21494); Hint superfamily (cl22434): Hedgehog/Intein domain; Colicin-DNase superfamily (cl15861); PLN02733 superfamily (cl22774): phosphatidylcholine-sterol O-acyltransferase; LysM superfamily (cl00107). RHS repeats (cl11982 & cl14012) [39].
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Francisella tularensis IglG BelongsFrancisella T 6SSα- helical N-terminal extensionFrancisella Pathogenicity IslandPAAR-Like T 6SS ProteinsUnique N-terminal Extensionnovicida intracellular life cycleN-terminal α- helical extensionT 6SStype VI secretion systemFPIDUF 4280 consensus protein sequenceT 6SS secretionT 6SS effector
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