A peptoid supramolecular host for benzo[<i>a</i>]pyrene in water

<p>Studies that identify a new supramolecular host for the highly toxic and prevalent carcinogen benzo[<i>a</i>]pyrene (BP) are reported here. By monitoring changes to absorption and fluorescence spectra, the interaction between BP and two peptoids (<i>N</i>-substituted glycine oligomers) of different length and self-association propensities were compared. Peptoid length and solvent choice influence spectral features. Observed trends support that peptoid self-association in aqueous solution generates a hydrophobic core to which BP can associate.</p>