A new sesquiterpene from the gorgonian coral <i>Menella</i> sp.

<p>A new sesquiterpene named menecubebane B (1) and a known analogue (2) were isolated from the gorgonian coral <i>Menella</i> sp. Their structures were elucidated by the extensive analyses of spectroscopic data and by the comparison with related literature. Cytotoxic effect against both Eca9706 and HeLa cell lines was evaluated, revealing 1 exhibited moderate cytotoxicity against the two cell lines involved with IC<sub>50</sub> values being 20.8 and 30.6 μM, respectively.</p>