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A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands

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posted on 2016-10-20, 08:10 authored by Clyde Gorapava Puilingi, Yuta Kudo, Yuko Cho, Keiichi Konoki, Mari Yotsu-Yamashita

A new sarasinoside congener (sarasinoside M2) and known sarasinoside B1 were obtained from a marine sponge. Sarasinoside M2 was suggested to have the same aglycon as sarasinoside M although the internal glucose in its sugar moiety is replaced by xylose. Sarasinosides B1 and M2 showed moderate cytotoxicity (approximate IC50 5–18 μM) toward Neuro-2a and HepG2 cell lines.

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    Bioscience, Biotechnology, and Biochemistry

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