A new naphthalene glycoside from the sponge-derived fungus <i>Arthrinium</i> sp. ZSDS1-F3

<div><p>One new naphthalene derivative, 1,8-dihydroxynaphthol-1-<i>O</i>-α-l-rhamnopyranoside (<b>1</b>), together with one known α-dibenzopyrone, alternariol (<b>2</b>), and five xanthones (<b>3</b>–<b>7</b>) were isolated from the sponge-derived fungus <i>Arthrinium</i> sp. ZSDS1-F3. All the isolated compounds (<b>1</b>–<b>7</b>) were established by comprehensive analysis of the spectral data, especially 1D and 2D NMR (HMQC and HMBC) spectra. In the primary bioassays, compound <b>3</b> exhibited moderate COX-2 inhibition, with IC<sub>50</sub> values of 12.2 μM.</p></div>