jo100859y_si_003.cif (14.38 kB)
A Highly Convergent Synthesis of Tricyclic N-Heterocycles Coupling an Ugi Reaction with a Tandem SN2′-Heck Double Cyclization
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posted on 2010-08-06, 00:00 authored by Renata Riva, Luca Banfi, Andrea Basso, Valentina Cerulli, Giuseppe Guanti, Marcella PaniA small library of natural product-like compounds has been assembled by coupling an Ugi multicomponent reaction with two postcondensation transformations, carried out in one-pot fashion: a SN2′ cyclization followed by an intramolecular Heck reaction.
