Fig 4.tif (692.02 kB)
ARCE prevented ISO induced modulations in gene expressions in rat heart tissues.
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posted on 2017-08-01, 17:34 authored by Sarmita Jana, Dipak Patel, Shweta Patel, Kapil Upadhyay, Jaymesh Thadani, Rahul Mandal, Santasabuj Das, Ranjitsinh DevkarThe total RNA isolated from heart tissues from rats of various treatment groups were subjected to cDNA synthesis and followed by quantitative PCR for (A) antioxidant genes (sod and catalase), (B) pro-apoptotic (bax) and anti-apoptotic (bcl-2) genes and (C) myocardium specific caveolin-3 and SERCA2a were analysed by quantitative PCR. The data were represented as mean ± SEM, two independent experiments, n = 6 in each experiments. **P<0.01 and *P<0.05 vs. control group; ##P<0.01 and #P<0.05 vs. ISO group.
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body weight ratioRats pretreatedMolecular docking scorescontrol groupfavourable heartcalcium imbalanceISO treatmentARCE pretreatmentBrassica oleracea LmRNA levelsapoptotic genesbcl -2study elucidatesmembrane damageSERCA 2a expressionH 9c cellsH 2 O 230 daysLigPlot analysisβ 1 adrenergic receptorrodent modelh 2 O 2infarction Cardioprotectivecaveolin -3
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