12-<i>Epi</i>-9-deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral, <i>Xenia</i> sp.
2017-12-05T08:50:40Z (GMT) by
<p>One new compound, 12-<i>epi</i>-9-deacetoxyxenicin (<b>1</b>) along with a hydroperoxide product, 12-<i>epi</i>-9-deacetoxy-8-hydroperoxyxenicin (<b>2</b>) and two known sesquiterpenoids (<b>3</b>–<b>4</b>) were isolated from a population of Bornean soft coral <i>Xenia</i> sp. The structures of these secondary metabolites were elucidated based on their spectroscopic data. Compounds <b>1</b> and <b>2</b> showed cytotoxic activity against ATL cell line, S1T. In addition, compound <b>3</b> exhibited hyphal inhibition of <i>Lagenidium thermophilum</i>.</p>