11-Isopropylcryptolepine:  A Novel Alkaloid Isolated from Cryptolepis
sanguinolenta Characterized Using Submicro NMR Techniques

Hadden, Chad E.; Sharaf, Maged H. M.; Guido, Jane E.; Robins, Russell H.; Tackie, Albert N.; Phoebe,, Charles H.; Schiff,, Paul L.; Martin, Gary E.

doi:10.1021/np980278t.s001

np980278t_si_001.pdf (47.34 kB)

11-Isopropylcryptolepine: A Novel Alkaloid Isolated from Cryptolepis sanguinolenta Characterized Using Submicro NMR Techniques

journal contribution

posted on 1998-12-09, 00:00 authored by Chad E. Hadden, Maged H. M. Sharaf, Jane E. Guido, Russell H. Robins, Albert N. Tackie, Charles H. Phoebe,, Paul L. Schiff,, Gary E. Martin

A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.