posted on 2013-02-19, 18:17authored byRefik Pul, Franco Morbiducci, Jelena Škuljec, Thomas Skripuletz, Vikramjeet Singh, Ute Diederichs, Niklas Garde, Elke Verena Voss, Corinna Trebst, Martin Stangel
A–D. Immunocytochemistry showed distinct phagocytosis of polystyrene beads (green) by monocytes treated with 31.25 µg/ml glatiramer acetate (GA) for 24 h (red, labelled with anti-CD14 antibody) as compared to medium, human serum albumin (HA), and mannitol (Mt) vehicle control. Scale bar: 50 µm. E. Representative z-stack series of confocal microscopic images demonstrate that the particles were completely internalised and not merely attached to the outer membrane. Scale bar: 10 µm.