Figure_4.tif (201.54 kB)
The Hirudin anticoagulated WBA exhibits high reliability upon repeated testing of the same donor.
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posted on 2013-08-05, 02:29 authored by Christoph Coch, Christian Lück, Anna Schwickart, Bastian Putschli, Marcel Renn, Tobias Höller, Winfried Barchet, Gunther Hartmann, Martin SchleeWhole blood of three different donors (a–c) anticoagulated with Hirudin was stimulated twice with one week inbetween with 0.8 µg/ml CpG 2006 delivered with polyethylenimine (PEI) or DOTAP. C20-DNA served as negative control. After 48 h supernatant was analyzed for IFN-α by ELISA. Mean of duplicates +/− SD is shown for each timepoint.
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Clinical immunologyImmune systemcytokinesimmunityImmune activationimmunoregulationimmunotherapyinflammationInnate immunityImmunologic techniquesimmunoassaysImmune responseDrugs and devicesDrug research and developmentdrug discoveryAdverse reactionsClinical pharmacologyPharmacodynamicstoxicologyImmunotoxicologyhirudinanticoagulatedwbaexhibitsrepeated
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