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The Early Phase of Pyroptosis Induced by Shigella Is Dependent on Ipaf but Not ASC

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posted on 2013-02-21, 12:07 authored by Toshihiko Suzuki, Luigi Franchi, Claudia Toma, Hiroshi Ashida, Michinaga Ogawa, Yuko Yoshikawa, Hitomi Mimuro, Naohiro Inohara, Chihiro Sasakawa, Gabriel Nuñez

Caspase-1-deficient (A and D), Ipaf-deficient (B and E), or ASC-deficient BMMs (C and F) were infected with Shigella WT (A–C) or TTSS mutant S325 (D–F). LDH released from infected BMMs were quantified at the indicated time. Error bars represent mean ± SD.

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