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Simplified scheme for the formation of germacrane, eudesmane and guaiane-type sesquiterpene lactones.

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posted on 2013-05-31, 00:06 authored by Aldana M. Ramirez, Nils Saillard, Ting Yang, Maurice C. R. Franssen, Harro J. Bouwmeester, Maarten A. Jongsma

The germacrane skeleton is formed from farnesyl diphosphate (FDP) and undergoes a cyclization reaction to either the guaiane or the eudesmane skeleton [43].

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