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Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.

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posted on 2013-02-21, 00:26 authored by Richa Tiwary, Weiping Yu, Jing Li, Sook-Kyung Park, Bob G. Sanders, Kimberly Kline

Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.

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