posted on 2013-03-01, 17:48authored byLauren Sullivan, Steven J. Wall, Mark Carrington, Michael A. J. Ferguson
Representative results using serum samples from a matched uninfected patient (left) and a stage 2 T. b. gambiense infected patient (right). The visual scores for these test lines were 0 and 5, respectively, and the CAMAG densitometry measurements were 24.2 and 597.4, respectively. The inset shows the principle of detection, with patient antibody to ISG65 forming a bridge between rISG56-1 immobilised on the nitrocellulose strip and the colloidal gold-coupled rISG65-1 picked up from the sample pad.