Table_1.xls (5.5 kB)
Pharmacokinetics parameters obtained from animals injected with a single dose of ceftiofur and PLGA-cef.
dataset
posted on 2015-04-27, 02:45 authored by Cristian Vilos, Luis A. Velasquez, Paula I. Rodas, Katherine Zepeda, Soung-Jae Bong, Natalia Herrera, Mario Cantin, Felipe Simon, Luis ConstandilNote: Data represent the mean ± standard deviation of serum values in rats (n = 3 per group) injected with free ceftiofur (700 μg/kg of weight), and PLGA-cef microparticles (10 mg/kg of weight).
Parameters: Cmax, maximal concentration; Tmax, time to maximal concentration; t1/2, elimination half-life; AUC, area under curve; α, constant of absorption; β, constant of elimination; A, rate constant representing slope of distribution; B, rate constant representing slope of elimination phase.
*Values with statistically significant differences (P<0.05, Mann–Whitney).
Pharmacokinetics parameters obtained from animals injected with a single dose of ceftiofur and PLGA-cef.
