Fig_4.tif (791.39 kB)
PPARγ antagonist blocked effects of MAG incubation on PPARγ expression and insulin-stimulated signaling pathway in human umbilical vein endothelial cells.
figure
posted on 2015-03-20, 02:49 authored by Xiangyan Liang, Wenjuan Xing, Jinxiao He, Feng Fu, Wei Zhang, Feifei Su, Fange Liu, Lele Ji, Feng Gao, Hui Su, Xin Sun, Haifeng ZhangRepresentative western blots showing PPARγ (A), TRB3 (B), phosphorylated Akt / Akt (C), and phosphorylated eNOS / eNOS (D), and NO release (E) in the conditioned medium. HG/HF, high glucose/high fat treatment; Mag, magnolol; BADGE, PPARγ antagonist bisphenol A diglycidyl ether (BADGE). All values are presented as mean ± SEM. n = 5–6. *P<0.05 vs. Control, #P<0.05 vs. HG/HF, $P<0.05 vs. HG/HF+BADGE.
