Mice survival and kinetics of parasitemia, anemia and leukocytes in blood of ED, LD and S mice infected with P. yoelii 17XL.

ICR mice infected with 2×10⁷ PyL iRBCs were classified as early deceased (ED), late deceased (LD) or surviving (S) depending on their (A) survival and parasitemia. *p<0.05 from ANOVA test. t-test was used to verify that significant differences were only between ED mice and the remaining groups. (B) Linear regression of the parasitemia of each mouse. *Significance between the mean 1/slope of each group. (C) Changes from baseline produced in circulating numbers of RBCs and WBC. *p<0.05 comparing to uninfected mice. Only one LD mouse was still alive on day 14 pi. Data express mean ± SEM of three independent experiments with n = 20.