LT imaging of AD propagating through thalamus and hypothalamus.

A) The AD front initiates medially and laterally (arrows) below the mammillo-thalamic tract (MT) at 3 minutes of OGD, before propagating dorsally and ventrally (arrows). At 4 minutes the ventral wave is joined by a weak wave from lateral hypothalamus that simultaneously engages PVN. At 5.6 minutes both PVNs swell (blue-white) which dissipates as thalamic injury develops (purple). AMV, anteromedial ventral thalamic nucleus; IAM, interoanteromedial nucleus; VA, ventroanterior nucleus; VM, ventromedial nucleus; F, fornix.