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LNA-antimiR-34a is associated with modest improvements in cardiac remodeling in a moderate model of pressure overload.
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posted on 2014-02-27, 04:21 authored by Bianca C. Bernardo, Xiao-Ming Gao, Yow Keat Tham, Helen Kiriazis, Catherine E. Winbanks, Jenny Y. Y. Ooi, Esther J. H. Boey, Susanna Obad, Sakari Kauppinen, Paul Gregorevic, Xiao-Jun Du, Ruby C. Y. Lin, Julie R. McMullen(A) Representative heart images of control, TAC moderate LNA control (CON) and TAC moderate LNA-antimiR-34a (anti-34a) at dissection. Scale bar = 0.5 cm. (B-D) Graphs of HW/TL, AW/TL and LW/TL. N = 4–8 per group. ***P<0.001 vs. control, **P<0.01 vs. control, *P<0.05 vs. control, †P<0.05. 1 way ANVOA followed by Fisher’s Post Hoc Test.
