Inhibition of CaMKKβ prevents baicalin-induced reduction in intracellular lipid accumulation in HeLa cells caused by oleic acid.

Cells were treated with 1 and 5 µM baicalin in the presence of 0.4 mM oleic acid for 24 hr without (open bars) or with pre-incubated with 10 µg/mL STO-609 (solid bars). The control cells were incubated with 1.76% bovine serum albumin (BSA) for 24 h. Intracellular triglyceride (TG, A) and intracellular cholesterol (TC, B) were measured as described in Material and Methods. The histogram represents the mean of the percentage of the vehicle control ± SE from at least three independent experiments. * p<0.05 compared to BSA control; ^# p<0.05 compared to untreated oleic acid control.