Influence of DMF and MMF on de- and remyelination in the corpus callosum.

Myelination in the corpus callosum was demonstrated by scoring of LFB-PAS stained sections (A) and the myelin proteins MBP (B), MOG (C), and PLP (D). In the corpus callosum score of 0 represents complete loss of myelin while score of 3 represents normal amount of myelin. Results are shown as means ± SEM. Significant post hoc effects versus controls (CO) are indicated by asterisks (*p<0.05, **p<0.01). In E1-G3 representative images of LFB-PAS stained sections of the corpus callosum are shown. Scale bars: 100 µm.