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Immunological responses in routine tuberculosis diagnostic tests following vaccination with BCG.

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posted on 2014-09-02, 04:51 authored by Natalie A. Parlane, Dairu Shu, Supatsak Subharat, D. Neil Wedlock, Bernd H. A. Rehm, Geoffrey W. de Lisle, Bryce M. Buddle
a

Caudal fold skin test positive defined as ≥1 mm increase in skin thickness.

b

PPD IFN-γ test positive defined as Bovine PPD OD – Avian PPD OD ≥0.100 OD.

c

ESAT-6/CFP10 IFN-γ test positive defined as ESAT-6/CFP10 (Antigen) OD -Nil (PBS) OD ≥0.040 OD NV, non-vaccinated BCG, BCG-vaccinated.

Immunological responses in routine tuberculosis diagnostic tests following vaccination with BCG.

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    lymph node lesion scoresBCG 2 yearsrevaccinated 2 yearsifnBCG vaccine 2½ yearsTB protein vaccinesESATTB protein vaccinevaccinationbovis culture filtrategroups vaccinated subcutaneouslycfuMycobacterium bovis 2½ years62 animals

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