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Immunohistochemical staining of term placenta serial sections including the basal plate.

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posted on 2013-02-20, 16:56 authored by Astrid Blaschitz, Martin Gauster, Dietmar Fuchs, Ingrid Lang, Petra Maschke, Daniela Ulrich, Eva Karpf, Osamu Takikawa, Michael G. Schimek, Gottfried Dohr, Peter Sedlmayr

IDO1 labelling results in staining of vascular endothelium, leaving villous and extravillous trophoblast unstained (A). The anti-CD34 antibody stains endothelial cells of the fetal circulation in the villous mesenchymal core and also endothelial cells which line the intervillous space; the arrowhead indicates a special site where endothelium connects with syncytiotrophoblast (B). HLA-G identifies extravillous cytotrophoblasts located in the basal plate (C). Scale bar represents 100 µm.

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