Figure_2.tif (4.23 MB)
Immunohistochemical staining of BLT1 and ALOX5 in human atherosclerotic plaques.
figure
posted on 2014-01-27, 03:30 authored by Pleunie van den Borne, Sander W. van der Laan, Sandra M. Bovens, Dave Koole, Mark C. Kowala, Laura F. Michael, Arjan H. Schoneveld, Sander M. van de Weg, Evelyn Velema, Jean-Paul de Vries, Gert J. de Borst, Frans L. Moll, Dominique P. V. de Kleijn, Paul H. A. Quax, Imo E. Hoefer, Gerard PasterkampBLT1 expression could mainly be observed in areas rich in (foamy) macrophages (A), in both a membranous and cytoplasmatic expression. A weaker expression of BLT1 could be observed in areas rich of SMCs (B). ALOX5 expression could predominantly be observed in areas rich in (foamy) macrophages (C), and around cholesterol clefts (D). Arrows indicate positive staining (brown color). Scale bar: 500 µm. The insert shows 5x extra magnification.
