posted on 2014-04-10, 04:28authored byJeffrey P. Perley, Judith Mikolajczak, Marietta L. Harrison, Gregery T. Buzzard, Ann E. Rundell
Arrow- and diamond-heads denote activation and inhibition of substrate molecules, respectively. TCR stimulation is achieved through αCD3 (green) binding. Subsequent Erk activation (black) controlled using small molecule inhibitors sanguinarine (blue) and U0126 (red).