Figure_1.tif (1.55 MB)
Exploratory comparison of MBD-seq and RRBS data.
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posted on 2013-03-16, 08:19 authored by Tim De Meyer, Evi Mampaey, Michaël Vlemmix, Simon Denil, Geert Trooskens, Jean-Pierre Renard, Sarah De Keulenaer, Pierre Dehan, Gerben Menschaert, Wim Van CriekingeVisual comparison of MBD-seq results for MethylMagnet (MMag), MethylCollector (MCol), MethylCollector Ultra (MCU), MethylCap (MCap) and MethylMiner (MMin) with RRBS data for the promoter regions of four selected loci, i.e. Igfbp3 (panel A, chromosome 7, depicted from position 45959883 to 45962146), Tert (panel B, chromosome 5, 1293850 to 1296219), Epb41l3 (panel C, chromosome 8, 5628365 to 5630973) and Socs3 (panel D, chromosome 17, 76354158 to 76357420). CpGs assessed by RRBS are indicated as vertical red (fraction methylated)/grey (fraction unmethylated) bars. Note that RRBS only assesses the methylation status of a (sometimes variable) subfraction of CpGs.
