Figure_1.tif (2.68 MB)
Electron micrographs of Plasmodium actin filaments.
figure
posted on 2014-04-17, 02:56 authored by Juha Vahokoski, Saligram Prabhakar Bhargav, Ambroise Desfosses, Maria Andreadaki, Esa-Pekka Kumpula, Silvia Muñico Martinez, Alexander Ignatev, Simone Lepper, Friedrich Frischknecht, Inga Sidén-Kiamos, Carsten Sachse, Inari Kursula(A) In the absence of stabilizing agents, actin I forms only short structures lacking helical symmetry. (B,C) Actin II readily forms filaments varying from hundreds of nm to 1–2 µm in length. (D,E) In the presence of JAS, both parasite actins form long helical filaments. (F) Length distributions of two Plasmodium actin isoforms and three actin I mutants. Note the logarithmic scale of the Y axis.
