Directed connectivity between frontal and parietal brain regions.

Fronto-parietal (F3–P3, F4–P4) (1a) and Fronto-occipital (F3–O1, F4–O2) (1b) directional connectivity during the awake (AWA) period compared to propofol-induced sedation (SED), propofol-induced loss of consciousness (LOC) and return of consciousness (ROC) after the termination of propofol infusion. The time frequency plot presents the number of subjects exceeding the significance level. Remark that the timeline between SED and LOC is almost continuous as all the subjects lost consciousness approximately 5 min after SED.