Figure_4.tif (674.38 kB)
C-peptide induced transcription factor ZEB DNA binding and Na,K-ATPase α1-subunit mRNA expression.
figure
posted on 2013-02-20, 11:08 authored by Dana Galuska, Sergej Pirkmajer, Romain Barrès, Karin Ekberg, John Wahren, Alexander V. ChibalinA. Exposure to 1 nM of C-peptide increased DNA binding activity of ZEB detected by EMSA. B. The electrophoretic mobility supershift assay with specific antibodies against ZEB. A–B. Experiments were performed at least 5 times and representative images are shown. C. mRNA expression of Na,K-ATPase α1-subunit. Results are means ± SE for 6 independent experiments. * P<0.05 versus 5 mM glucose without C-peptide.
