IL28B TG/GG, PNPLA3 CG/GG, and average ALT after interferon therapy ≥ 40 IU/l were scored as 1 point. Similarly, IL28B TT, PNPLA3 CC, and average ALT after interferon therapy < 40 IU/l were scored as 0 point. Patients scored 0–1, 2 and 3 were defined as a low, intermediate, and high risk group, respectively. Error bars indicate the standard error.