Anti-IL-10R treatment increases CD11b⁺Ly6C⁺ monocytic cell percentages and serum CCL2 concentration during T. brucei infection.

WT mice were treated with neutralizing anti-IL-10R antibody or control antibody on days 7 and 9 of infection and euthanized on day 10. A) Percentages of CD11b⁺Ly6C⁺ monocytic cells in the non-parenchymal liver cell fraction, blood and bone marrow of WT (white bars) and CCR2 KO (grey bars) mice with or without anti-IL-10R treatment. B) CCL2 protein concentration in blood sera of WT T. brucei infected mice. Data are the mean ± SEM of three individual mice tested in one of three independent experiments performed. *, significantly (p<0.05) higher compared to control treated WT mice.