Fig_6.tif (1.15 MB)
ANGPTL2 enhanced hepatic lipid accumulation in mice.
figure
posted on 2015-07-01, 04:45 authored by Yusuke Sasaki, Masayuki Ohta, Dhruv Desai, Jose-Luiz Figueiredo, Mary C. Whelan, Tomohiro Sugano, Masaki Yamabi, Wataru Yano, Tyler Faits, Katsumi Yabusaki, Hengmin Zhang, Andrew K. Mlynarchik, Keisuke Inoue, Ken Mizuno, Masanori AikawaA, Representative images of the liver (Left: LacZ, Right: Angptl2, db/db mice). B, Liver triglyceride levels (Left: Lean mice, Right: db/db mice, n = 7–8 animals per group). C, Representative images of oil red O staining (Left: LacZ, Right: Angptl2, db/db mice). D, Oil red O staining area (n = 7–8, db/db mice). E, Quantitative RT-PCR of mRNAs encoding genes related to fatty acid metabolism in the liver of lean mice (n = 8) F, Quantitative RT-PCR of mRNAs encoding genes related to fatty acid metabolism in the liver of db/db mice (n = 7–8). Data are mean ± SEM, **: P<0.01, *: P<0.05 compared with LacZ group.
