Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems

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Kohl, James V. (2014): Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. figshare.
Retrieved 22:20, Nov 25, 2015 (GMT)


This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA / messenger RNA balance and chromosomal rearrangements. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding; experience-dependent receptor-mediated behaviors, and organism-level thermoregulation in ever-changing ecological niches and social niches. Nutrient-dependent pheromone-controlled ecological, social, neurogenic and socio-cognitive niche construction are manifested in increasing organismal complexity in species from microbes to man. Species diversity is a biologically-based nutrient-dependent morphological fact and species-specific pheromones control the physiology of reproduction. The reciprocal relationships of species-typical nutrient-dependent morphological and behavioral diversity are enabled by pheromone-controlled reproduction. Ecological variations and biophysically constrained natural selection of nutrients cause the behaviors that enable ecological adaptations. Species diversity is ecologically validated proof-of-concept. Ideas from population genetics, which exclude ecological factors, are integrated with an experimental evidence-based approach that establishes what is currently known. This is known: Olfactory/pheromonal input links food odors and social odors from the epigenetic landscape to the physical landscape of DNA in the organized genomes of species from microbes to man during their development.


Comments (2)

  • http://www.scienc...9/supp/C
    The articles in this issue on Neuromodulation each appear to support the atoms to ecosystems model detailed in Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems http://figshare.c...s/994281

    Conserved molecular mechanisms establish the basis for 'conditions of life.'

    Anyone who would still like to try to link the pseudoscientific nonsense of population genetics to a theory of how mutations and natural selection lead to the evolution of nutrient-dependent pheromone-controlled biodiversity, can compare the ridiculous beliefs about biologically-based cause and effect that they have incorporated into their theories to biological facts that have not changed since Darwin attested to them in the context of his 'conditions of life,' which were subsequently ignored as neo-Darwinism was invented.

    Read more at:

    08/06/2014    by J. Kohl

  • See also: Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms

    My comment: The authors appear to confuse evolutionary pressures with facts about how ecological variation leads to ecological adaptations via conserved molecular mechanisms.

    The conserved molecular mechanisms are not potential mechanisms. They are the biophysically constrained nutrient-dependent pheromone-controlled epigenetically-effected molecular mechanisms that enable the chemistry of protein folding to link RNA-directed DNA methylation and RNA-mediated cell type differentiation to all cell types in all organisms of all species from microbes to man.

    08/11/2014    by J. Kohl

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